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  Indian J Med Microbiol
 

Figure 1: Effect of radiation on breast cancer cells through specific and nonspecific targeting. (a) Specific targeting leads to reduction in tumor volume, survival of resistant cells, formation of cancer stem cell formation (formation repetitive), or epigenetic changes. The latter can lead to radioresistance and/or cancer stem cell formation or reduced tumor volume. The radioresistant or cancer stem cell, later, are relevant to long-term source of metastasis such as recurrence. (b) Nonspecific targeting occurs when the radiation indirectly affects tumor cells or the tumor microenvironment for outcome described as for “A”

Figure 1: Effect of radiation on breast cancer cells through specific and nonspecific targeting. (a) Specific targeting leads to reduction in tumor volume, survival of resistant cells, formation of cancer stem cell formation (formation repetitive), or epigenetic changes. The latter can lead to radioresistance and/or cancer stem cell formation or reduced tumor volume. The radioresistant or cancer stem cell, later, are relevant to long-term source of metastasis such as recurrence. (b) Nonspecific targeting occurs when the radiation indirectly affects tumor cells or the tumor microenvironment for outcome described as for “A”