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Current Issue

April-June 2018| Vol 9| Issue 2

Review Article

Apurinic/apyrimidinic endonuclease 1 performs multiple roles in controlling the outcome of cancer cells toward radiation and chemotherapeutic agents

Many endogenous and exogenous sources produce reactive oxygen species such as superoxide radical anions and hydrogen peroxide that are converted to the highly reactive form, hydroxyl radical. It is th...

Original Article

The comparison of genetic instability in haploid and diploid yeast cells exposed to ionizing radiations of different linear energy transfer and ultraviolet light

Context: It is analyzed whether genetic instability is determined by cell ability to recover from radiation damage or it is mainly determined by cell ploidy. The values of the RBE of α-par...

Original Article

Valproic acid, a histone deacetylase inhibitor, enhances radiosensitivity in breast cancer cell line

Purpose: Valproic acid (VPA) is used mainly for the treatment of epilepsy and other seizure disorders, however, it is known to be one of histone deacetylase (HDAC) inhibitors. HDACIs have repre...

Original Article

Inhibitor of nonhomologous end joining can inhibit proliferation of diffuse large B-Cell lymphoma cells and potentiate the effect of ionization radiation

Aim: Diffuse large B-cell lymphoma (DLBCL) is the most common and aggressive type of non-Hodgkin's lymphoma that accounts for ~40% of all lymphomas. DLBCL is considered to be clinically...

Technical Report

A systematic organization of bioinformatics database of radiosensitizers and radioprotectors

Radiosensitizers and radioprotectors are the compounds that modify the radiation therapy treatment. Radiosensitizers make tumor cell more sensitive to radiation therapy which increases the effectivene...

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Journal of Radiation and Cancer Research, a publication of Society for Radiation Research, is a peer-reviewed online journal with Quarterly print on demand compilation of issues published. The journal’s full text is available online at http://www.journalrcr.org

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